LIPASE-CATALYZED KINETIC RESOLUTION OF (+/-)-2-HYDROXYMETHYL-1,4-BENZODIOXANE

被引:22
作者
ANTUS, S
GOTTSEGEN, A
KAJTAR, J
KOVACS, T
TOTH, TS
WAGNER, H
机构
[1] L EOTVOS UNIV,INST ORGAN CHEM,H-1518 BUDAPEST 112,HUNGARY
[2] UNIV MUNICH,INST PHARMAZEUT BIOL,W-8000 MUNICH 2,GERMANY
关键词
D O I
10.1016/S0957-4166(00)86078-4
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The title compound has been kinetically resolved in a lipase-catalyzed transesterification with vinyl acetate in organic solvents. The influence of the enzyme source as well as the character of the solvent on the enantioselectivity has been studied.
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页码:339 / 344
页数:6
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