NMR EVIDENCE FOR THE DISPLACEMENT OF A CONSERVED INTERIOR WATER MOLECULE IN HIV PROTEASE BY A NONPEPTIDE CYCLIC UREA-BASED INHIBITOR

被引：52

作者：

GRZESIEK, S

BAX, A

NICHOLSON, LK

YAMAZAKI, T

WINGFIELD, P

STAHL, SJ

EYERMANN, CJ

TORCHIA, DA

HODGE, CN

LAM, PYS

JADHAV, PK

CHANG, CH

机构：

[1] NIDDKD,CHEM PHYS LAB,BETHESDA,MD 20892

[2] NIDR,BONE RES BRANCH,BETHESDA,MD 20892

[3] NIH,PROT EXPRESS LAB,BETHESDA,MD 20892

[4] DUPONT MERCK PHARMACEUT CO,DEPT VIROL,WILMINGTON,DE 19880

[5] DUPONT MERCK PHARMACEUT CO,DEPT CHEM & PHYS SCI,WILMINGTON,DE 19880

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1994年 / 116卷 / 04期

关键词：

D O I：

10.1021/ja00083a058

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：1581 / 1582

页数：2

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