THE ROLE OF NATURAL-KILLER-CELLS IN TRANSPLANTATION

被引：30

作者：

LANIER, LL

机构：

[1] DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 05期

关键词：

D O I：

10.1016/0952-7915(95)80068-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Natural killer cells express receptors for polymorphic MHC class I molecules that inhibit cytotoxicity mediated by natural killer cells. The genes encoding the mouse and human natural killer cell receptors for MHC class I have recently been cloned, and there is rapid progress in elucidating their structure and function. These receptors may be important in bone marrow transplantation and explain the phenomenon of hybrid resistance.

引用

收藏

页码：626 / 631

页数：6

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