OCCURRENCE OF SIALIC ACIDS IN DROSOPHILA-MELANOGASTER

被引：147

作者：

ROTH, J

KEMPF, A

REUTER, G

SCHAUER, R

GEHRING, WJ

机构：

[1] UNIV BASEL,BIOCTR,DEPT CELL BIOL,CH-4056 BASEL,SWITZERLAND

[2] UNIV KIEL,INST BIOCHEM,W-2300 KIEL 1,GERMANY

来源：

SCIENCE | 1992年 / 256卷 / 5057期

关键词：

D O I：

10.1126/science.1585182

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Sialylated oligosaccharides, which are cell type-specific and developmentally regulated, have been implicated in a variety of complex biological events. Their broad functional importance is reflected by their presence in a wide variety of phyla extending from Echinodermata through higher vertebrates. Here, sialic acids are detected throughout development in an insect, Drosophila. Homopolymers of alpha-2,8-linked sialic acid, polysialic acid, are developmentally regulated and only expressed during early Drosophila development.

引用

页码：673 / 675

页数：3

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