ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA IN A RENAL-TRANSPLANT PATIENT WITH EVIDENCE OF EPSTEIN-BARR-VIRUS INVOLVEMENT

被引：28

作者：

BORISCH, B ^{[1
]}

HENNIG, I ^{[1
]}

HORBER, F ^{[1
]}

BURKI, K ^{[1
]}

LAISSUE, J ^{[1
]}

机构：

[1] UNIV BERN,DEPT OUTPATIENT INTERNAL MED,CH-3010 BERN,SWITZERLAND

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1992年 / 421卷 / 05期

关键词：

ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA; EPSTEIN-BARR VIRUS; EPSTEIN-BARR VIRUS RNA INSITU; POLYMERASE CHAIN REACTION; RENAL TRANSPLANTATION;

D O I：

10.1007/BF01606918

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The clinical and histological findings in a 54-year-old patient with enteropathy-associated T-cell lymphoma (EATL) occurring 18 years after renal transplantation are presented. Ten years after adult-onset coeliac disease the patient developed medium to large T-cell non-Hodgkin's lymphoma of the small intestine. Epstein-Barr virus (EBV) genome was detected by polymerase chain reaction in the lymphoma tissue and localized via Epstein-Barr virus RNAs in situ hybridization to some of the tumour cells. This is the first case report of EBV-positive EATL occuring in the setting of immunosuppression.

引用

页码：443 / 447

页数：5