DONOR-ACCEPTOR CHIRAL CENTRIFUGAL PARTITION CHROMATOGRAPHY - COMPLETE RESOLUTION OF 2 PAIRS OF AMINO-ACID DERIVATIVES WITH A CHIRAL-II DONOR SELECTOR

被引：23

作者：

OLIVEROS, L

PUERTOLAS, PF

MINGUILLON, C

CAMACHOFRIAS, E

FOUCAULT, A

LEGOFFIC, F

机构：

[1] UNIV BARCELONA,FAC FARM,QUIM FARMACEUT LAB,E-08028 BARCELONA,SPAIN

[2] CNRS,ERS 71,BIOORGAN & BIOTECHNOL LAB,F-75005 PARIS,FRANCE

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1994年 / 17卷 / 11期

关键词：

D O I：

10.1080/10826079408013481

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Two racemic compounds, namely N-(3,5-dinitrobenzoyl)-tert-butylvallnamide, and N-(3,5-dinitrobenzoyl)-tert-butylleucinamide, have been successfully completely resolved by centrifugal partition chromatography, using N-dodecanoyl-L-Proline-3,5-dimethylanilide as a chiral selector, and a biphasic system made with heptane, ethyl acetate. methanol and water. This opens the way to a better understanding of this class of separation by centrifugal partition chromatography.

引用

页码：2301 / 2318

页数：18

共 24 条

[1]

AHUJA S, 1991, ACS SYM SER, V471, pCH1

[2]

ARAL T, 1991, CHROMATOGRAPHIA, V32, P56

[3] STUDY OF THE ORIGIN AND MECHANISM OF BAND BROADENING AND PRESSURE-DROP IN CENTRIFUGAL COUNTERCURRENT CHROMATOGRAPHY [J].