IN-VITRO EVOLUTION OF NUCLEIC-ACIDS

被引:119
作者
JOYCE, GF [1 ]
机构
[1] SCRIPPS RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA
关键词
D O I
10.1016/S0959-440X(94)90100-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An increasing number of laboratories are applying the principles of Darwinian evolution to large populations of RNA or DNA molecules to obtain compounds that bind a target ligand or catalyze a particular chemical reaction. These molecules may be useful as enzyme inhibitors or diagnostic agents.
引用
收藏
页码:331 / 336
页数:6
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