IBUPROFEN, A UNIQUE ANTIINFLAMMATORY COMPOUND WITH ANTIFUNGAL ACTIVITY AGAINST DERMATOPHYTES

被引：48

作者：

SANYAL, AK

ROY, D

CHOWDHURY, B

BANERJEE, AB

机构：

[1] University College of Science, Department of Biochemistry, Microbiology Laboratory, Calcutta, 700 019

来源：

LETTERS IN APPLIED MICROBIOLOGY | 1993年 / 17卷 / 03期

关键词：

D O I：

10.1111/j.1472-765X.1993.tb01436.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Ibuprofen showed significant antifungal activity in vitro against dermatophytes at pH 5 (MIC: 5-40 mug ml-1). In this respect it is comparatively more efficient than two well known and medically used antifungal compounds, benzoic and salicylic acids. This compound with anti-inflammatory activity which is not found in any other conventional antifungal organic acids, may have clinical prospects.

引用

页码：109 / 111

页数：3