EXPERIMENTAL SLEEP FRAGMENTATION

被引:106
作者
ROEHRS, T
MERLOTTI, L
PETRUCELLI, N
STEPANSKI, E
ROTH, T
机构
[1] Henry Ford Hospital, Detroit, MI 48202
关键词
SLEEP FRAGMENTATION; BRIEF AROUSALS; DAYTIME SLEEPINESS/ALERTNESS; MULTIPLE SLEEP LATENCY TEST;
D O I
10.1093/sleep/17.5.438
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Thirty-six healthy young men and women (age range 21-35 years) were studied in an experimental model of sleep fragmentation. On 2 nights sleep was disrupted by presenting tones to produce brief electroencephalogram (EEG) arousals (without shortening sleep time) and daytime function was assessed the following day with the Multiple Sleep Latency Test and a divided attention performance test. The fragmentation of sleep produced significant disruption of nocturnal sleep and reduced daytime alertness. Adaptation in EEG-defined arousals occurred from the Ist to the 2nd night of fragmentation. Threshold (measured indirectly) characteristics of EEG-defined arousals were somewhat different than those of previous studies requiring behavioral awakening. The percent of tone series producing arousal, number of tones necessary for arousal and duration of the arousal all reflected heightened thresholds in stage 3/4 and rapid eye movement (REM) sleep compared to stage 1 and stage 2 sleep. In the last 3 hours of sleep versus the first 3 hours, arousals occurred less frequently, required more tones to produce, resulted in shorter durations and in fewer deep stage changes, except for REM sleep where the converse was the case.
引用
收藏
页码:438 / 443
页数:6
相关论文
共 20 条
[11]   EFFECTS OF EXPERIMENTALLY-INDUCED SLEEP FRAGMENTATION ON SLEEP AND SLEEPINESS [J].
MAGEE, J ;
HARSH, J ;
BADIA, P .
PSYCHOPHYSIOLOGY, 1987, 24 (05) :528-534
[12]   AUDITORY AWAKENING THRESHOLDS IN REM AND NREM SLEEP STAGES [J].
RECHTSCH.A ;
HAURI, P ;
ZEITLIN, M .
PERCEPTUAL AND MOTOR SKILLS, 1966, 22 (03) :927-&
[13]  
Rechtschaffen A., 1968, NAT I HLTH PUBLICATI
[14]   PERIODIC MOVEMENTS DURING SLEEP, SLEEP FRAGMENTATION, AND SLEEP-WAKE COMPLAINTS [J].
ROSENTHAL, L ;
ROEHRS, T ;
SICKLESTEEL, J ;
ZORICK, F ;
WITTIG, R ;
ROTH, T .
SLEEP, 1984, 7 (04) :326-330
[15]  
ROTH T, 1980, SLEEP, V3, P425
[16]   SLEEP FRAGMENTATION AND DAYTIME SLEEPINESS [J].
STEPANSKI, E ;
LAMPHERE, J ;
BADIA, P ;
ZORICK, F ;
ROTH, T .
SLEEP, 1984, 7 (01) :18-26
[17]   EXPERIMENTAL SLEEP FRAGMENTATION IN NORMAL SUBJECTS [J].
STEPANSKI, E ;
LAMPHERE, J ;
ROEHRS, T ;
ZORICK, F ;
ROTH, T .
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 1987, 33 (3-4) :207-214
[18]   AUDITORY AWAKENING THRESHOLDS AND DREAM RECALL IN NREM SLEEP [J].
WATSON, R ;
RECHTSCH.A .
PERCEPTUAL AND MOTOR SKILLS, 1969, 29 (02) :635-&
[19]   RESPONSES TO AUDITORY STIMULATION SLEEP LOSS + EEG STAGES OF SLEEP [J].
WILLIAMS, HL ;
LUBIN, A ;
DALY, RL ;
HAMMACK, JT ;
DEMENT, WC .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1964, 16 (03) :269-&
[20]  
1992, SLEEP, V15, P173