EFFECT OF THIOPENTONE, ETOMIDATE AND PROPOFOL ON SYSTEMIC VASCULAR-RESISTANCE DURING CARDIOPULMONARY BYPASS

被引：35

作者：

BOER, F

BOVILL, JG

ROS, P

VANOMMEN, H

机构：

[1] Department of Anaesthesiology, University Hospital Leiden, 2300 RC Leiden

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1991年 / 67卷 / 01期

关键词：

ANESTHETIC; INTRAVENOUS; PROPOFOL; THIOPENTONE; ETOMIDATE; HEART; VASCULAR PRESSURES;

D O I：

10.1093/bja/67.1.69

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We have studied the effect of thiopentone, etomidate and propofol on systemic vascular resistance (SVR) during cardiopulmonary bypass with constant pump flow in 30 patients undergoing elective coronary artery bypass surgery. SVR decreased to 78% of control values after thiopentone 4 mg kg-1, to 72% of control after etomidate 0.3 mg kg-1, and to 68% of control after propofol 2 mg kg-1; it returned to control values 10 min after administration of thiopentone and propofol and 7 min after administration of etomidate. Analysis of variance showed that there were no significant differences in the changes in SVR between the groups.

引用

页码：69 / 72

页数：4

共 23 条

[11] PHARMACOKINETICS AND PLASMA-BINDING OF THIOPENTAL .1. STUDIES IN SURGICAL PATIENTS [J].