ELECTRIC FIELD-INDUCED ORIENTATION OF RAT HIPPOCAMPAL-NEURONS INVITRO

被引:47
作者
RAJNICEK, AM [1 ]
GOW, NAR [1 ]
MCCAIG, CD [1 ]
机构
[1] UNIV ABERDEEN MARISCHAL COLL,DEPT MOLEC & CELL BIOL,ABERDEEN AB9 1AS,SCOTLAND
基金
英国惠康基金;
关键词
D O I
10.1113/expphysiol.1992.sp003580
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Rat hippocampal neurones in primary culture exhibited directional growth in response to DC electric fields. Neurites lay perpendicular to the field after exposure to 28, 80 or 219 mV/mm but there was no orientation effect at 9 mV/mm or in unexposed control cultures. Fields that evoked perpendicular responses also reduced the number of cathode-facing neurites. Orientation was the same for neurite initiation sites and the direction of overall neurite growth.
引用
收藏
页码:229 / 232
页数:4
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