A G-PROTEIN INVOLVED IN NUCLEOCYTOPLASMIC TRANSPORT - THE ROLE OF RAN

被引：134

作者：

MOORE, MS

BLOBEL, G

机构：

[1] M. S. Moore and G. Blobel are, the Rockefeller University, Howard Hughes Medical Institute, New York, NY 10021

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1994年 / 19卷 / 05期

关键词：

D O I：

10.1016/0968-0004(94)90024-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ran is the only known member of the Ras superfamily of small GTP-binding proteins to be localized primarily inside the nucleus. Recently, Ran was unexpectedly identified as one of the soluble factors required for nuclear import. As this protein has also been implicated in RNA export, nuclear import and export may be more closely related than previously thought, with Ran playing a key role in each.

引用

页码：211 / 216

页数：6

共 27 条

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