TUMOR LOCALIZING AGENTS .7. RADIOIODINATED QUINOLINE DERIVATIVES

被引：24

作者：

COUNSELL, RE

POCHA, P

RANADE, VV

STERNGOLD, J

BEIERWALTES, WH

机构：

[1] Laboratory of Medicinal Chemistry, College of Pharmacy, Department of Medicine (Nuclearr Medicine), University of Michigan, Ann Arbor

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 02期

关键词：

D O I：

10.1021/jm00302a009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Several radioiodinated analogs of chloroquiiio were synthesized in an effort-to find an agent which would selectively localize in melanomas. One compound, 4-(3-dimethylamiiiopvopylanmino)-7-iodoquinoline-125I was found to have a marked affinity for melanin-containing tissues and for melanotic tumors in animals. © 1969, American Chemical Society. All rights reserved.

引用

页码：232 / +

页数：1