GTP ANALOGS CAUSE RELEASE OF THE ALPHA-SUBUNIT OF THE GTP BINDING-PROTEIN, GO, FROM THE PLASMA-MEMBRANE OF NG108-15 CELLS

被引：45

作者：

MCARDLE, H

MULLANEY, I

MAGEE, A

UNSON, C

MILLIGAN, G

机构：

[1] UNIV GLASGOW,DEPT BIOCHEM,MOLEC PHARMACOL GRP,GLASGOW G12 8QQ,SCOTLAND

[2] UNIV GLASGOW,DEPT PHARMACOL,GLASGOW G12 8QQ,SCOTLAND

[3] NATL INST MED RES,LONDON NW7 1AA,ENGLAND

[4] ROCKEFELLER UNIV,DEPT BIOCHEM,NEW YORK,NY 10021

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1988年 / 152卷 / 01期

关键词：

D O I：

10.1016/S0006-291X(88)80706-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：243 / 251

页数：9

共 18 条

[1] MYRISTOYLATED ALPHA-SUBUNITS OF GUANINE NUCLEOTIDE-BINDING REGULATORY PROTEINS [J].

BUSS, JE ;

MUMBY, SM ;

CASEY, PJ ;

GILMAN, AG ;

SEFTON, BM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (21) :7493-7497

[2] GTP-BINDING PROTEINS IN BRAIN AND NEUTROPHIL ARE TETHERED TO THE PLASMA-MEMBRANE VIA THEIR AMINO TERMINI [J].

EIDE, B ;

GIERSCHIK, P ;

MILLIGAN, G ;

MULLANEY, I ;

UNSON, C ;

GOLDSMITH, P ;

SPIEGEL, A .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 148 (03) :1398-1405

[3] ABOLITION OF THE EXPRESSION OF INHIBITORY GUANINE-NUCLEOTIDE REGULATORY PROTEIN-GI ACTIVITY IN DIABETES [J].

GAWLER, D ;

MILLIGAN, G ;

SPIEGEL, AM ;

UNSON, CG ;

HOUSLAY, MD .

NATURE, 1987, 327 (6119) :229-232

[4] USE OF SPECIFIC ANTIBODIES TO QUANTITATE THE GUANINE NUCLEOTIDE-BINDING PROTEIN-G0 IN BRAIN [J].

GIERSCHIK, P ;

MILLIGAN, G ;

PINES, M ;

GOLDSMITH, P ;

CODINA, J ;

KLEE, W ;

SPIEGEL, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (07) :2258-2262

[5]

GOLDSMITH P, 1987, J BIOL CHEM, V262, P14683

[6] THE GTP-BINDING PROTEIN, G0, REGULATES NEURONAL CALCIUM CHANNELS [J].

HESCHELER, J ;

ROSENTHAL, W ;

TRAUTWEIN, W ;

SCHULTZ, G .

NATURE, 1987, 325 (6103) :445-447

[7]

JONES DT, 1987, J BIOL CHEM, V262, P14241

[8] IDENTIFICATION OF SPECIFIC TRANSDUCIN ALPHA-SUBUNITS IN RETINAL ROD AND CONE PHOTORECEPTORS [J].

LEREA, CL ;

SOMERS, DE ;

HURLEY, JB ;

KLOCK, IB ;

BUNTMILAM, AH .

SCIENCE, 1986, 234 (4772) :77-80

[9] ALPHA-SUBUNITS OF NS ARE RELEASED FROM THE PLASMA-MEMBRANE FOLLOWING CHOLERA-TOXIN ACTIVATION [J].

LYNCH, CJ ;

MORBACH, L ;

BLACKMORE, PF ;

EXTON, JH .

FEBS LETTERS, 1986, 200 (02) :333-336

[10] ANTIBODIES WHICH RECOGNIZE THE C-TERMINUS OF THE INHIBITORY GUANINE-NUCLEOTIDE-BINDING PROTEIN (GI) DEMONSTRATE THAT OPIOID-PEPTIDES AND FETAL-CALF SERUM STIMULATE THE HIGH-AFFINITY GTPASE ACTIVITY OF 2 SEPARATE PERTUSSIS-TOXIN SUBSTRATES [J].

MCKENZIE, FR ;

KELLY, ECH ;

UNSON, CG ;

SPIEGEL, AM ;

MILLIGAN, G .

BIOCHEMICAL JOURNAL, 1988, 249 (03) :653-659

← 1 2 →