SYNTHESIS OF PHOSPHOLIPIDS AND TRIGLYCERIDES IN HUMAN LIVER SLICES .I. EXPERIMENTAL CONDITIONS AND SYNTHESIS RATE IN NORMAL LIVER TISSUE

被引：50

作者：

NILSSON, S

SCHERSTEN, T

机构：

[1] Department of Surgery II Sahlgrenska sjukhuset, University of Göteborg, Göteborg

来源：

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | 1969年 / 24卷 / 03期

关键词：

Glycerol metabolism; Lipid metabolism; Lipid synthesis; Liver; Liver slices; Phospholipid synthesis; Triglyceride synthesis;

D O I：

10.3109/00365516909080159

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Human liver slices were incubated with glycerol-1,3-14C or fructose-U-14C. 50% of the label was recovered as glucose and 10% was incorporated into CO2 and into lipids, respectively. At high fatty acid concentration in the medium the incorporation into CO2 and glucose was suppressed, into triglycerides increased, and into phospholipids unchanged. The incorporation of fructose was suppressed with glycerol in the medium. The mean synthesis rate for phospholipids was 0.14 ± 0.01 μmoles/g liver per hour and for triglycerides 0.34 ± 0.04 μmoles/g liver per hour. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：237 / +

页数：1