SIGNAL TRANSDUCTION AND THE FATE OF THE R7 PHOTORECEPTOR IN DROSOPHILA

被引：151

作者：

RUBIN, GM ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,DEPT MOLEC & CELL BIOL,BERKELEY,CA 94720

来源：

TRENDS IN GENETICS | 1991年 / 7卷 / 11-12期

关键词：

D O I：

10.1016/0168-9525(91)90258-R

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The sevenless protein tyrosine kinase receptor plays a central role in the pathway of cell fate induction that determines the development of the R7 photoreceptor in the Drosophila eye. In the last year we have learned much about the probable ligand for sevenless and have begun to dissect the signal transduction pathway that relays the information from the sevenless kinase. Studies of the mechanisms governing the specificity of signal transmission and reception suggest that the sevenless signal directs a bipotential cell towards a neuronal rather than a cone cell fate.

引用

页码：372 / 377

页数：6