HPLC DETERMINATION OF TOCOPHEROL, RETINOL, DEHYDRORETINOL AND RETINYL PALMITATE IN TISSUES OF LAKE CHAR (SALVELINUS-NAMAYCUSH) EXPOSED TO COPLANAR 3,3',4,4',5-PENTACHLOROBIPHENYL

被引：55

作者：

PALACE, VP ^{[1
]}

BROWN, SB ^{[1
]}

机构：

[1] FISHERIES & OCEANS CANADA, WINNIPEG R3T 2N6, MANITOBA, CANADA

来源：

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY | 1994年 / 13卷 / 03期

关键词：

VITAMIN-E; VITAMIN-A; RETINOIDS; COPLANAR PCB;

D O I：

10.1002/etc.5620130315

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Tocopherol, retinol, dehydroretinol, and retinyl palmitate were measured by reversed-phase HPLC in liver, kidney, and plasma of lake char exposed to orally administered coplanar 3,3,4,4,5-pentachlorobiphenyl (PCB). Tocopherol concentrations were unaffected after eight weeks. Liver retinol, dehydroretinol, and retinyl palmitate concentrations were lower, whereas kidney retinyl palmitate was elevated in PCB-exposed groups. Tissue retinoid concentrations provide sensitive indicators of coplanar PCB exposure in fish.

引用

页码：473 / 476

页数：4

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