SYNTHESIS OF ANGIOTENSINS, BRADYKININS AND SUBSTANCE-P OCTAPEPTIDES IN WHICH THE RESIDUES PHE AND TYR HAVE BEEN REPLACED WITH CAR AND OF [CAR1,LEU5]-ENKEPHALIN

Thirteen peptides, analogues of bradykinin (BK), enkephalin, Substance P (SP) and [Sar1]‐angiotensin II ([Sar1]‐ATII) have been synthesized by the solid‐phase method. In all these peptides the residue Phe and Tyr were substituted with the boron‐containing amino‐acid L‐o‐carboranylalanine (Car). The purity and identity of the peptides were established by TLC., cellulose‐electrophoresis and amino acid analysis. Copyright © 1979 Verlag GmbH & Co. KGaA, Weinheim