SYNTHESIS OF ANGIOTENSINS, BRADYKININS AND SUBSTANCE-P OCTAPEPTIDES IN WHICH THE RESIDUES PHE AND TYR HAVE BEEN REPLACED WITH CAR AND OF [CAR1,LEU5]-ENKEPHALIN

被引：34

作者：

LEUKART, O

ESCHER, E

REGOLI, D

机构：

[1] UNIV SHERBROOKE,SCH MED,DEPT PHYSIOL & PHARMACOL,SHERBROOKE J1H 5N4,QUEBEC,CANADA

[2] ETH HONGGERBERG,INST MOLEC BIOL & BIOPHYS,ZURICH,SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1979年 / 62卷 / 02期

关键词：

D O I：

10.1002/hlca.19790620223

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thirteen peptides, analogues of bradykinin (BK), enkephalin, Substance P (SP) and [Sar1]‐angiotensin II ([Sar1]‐ATII) have been synthesized by the solid‐phase method. In all these peptides the residue Phe and Tyr were substituted with the boron‐containing amino‐acid L‐o‐carboranylalanine (Car). The purity and identity of the peptides were established by TLC., cellulose‐electrophoresis and amino acid analysis. Copyright © 1979 Verlag GmbH & Co. KGaA, Weinheim

引用

页码：546 / 552

页数：7

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