SOLID-PHASE SYNTHESES OF UNNATURAL BIOPOLYMERS CONTAINING REPEATING UREA UNITS

被引：156

作者：

BURGESS, K ^{[1
]}

LINTHICUM, DS ^{[1
]}

SHIN, HW ^{[1
]}

机构：

[1] TEXAS A&M UNIV,COLL VET MED,COLLEGE STN,TX 77843

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 08期

关键词：

SOLID-PHASE SYNTHESES; UREA;

D O I：

10.1002/anie.199509071

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New “oligourea”‐based peptidomimetics are the subject of this communication. Two new derivatives of this type, including the Leu‐enkephalin analog 1, have been prepared by addition of suitably protected isocyanates to amino acids supported on Rink's amide resin. The chemistry described is designed for solid‐phase approaches to combinatorial libraries by split syntheses. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：907 / 909

页数：3