TITYUS-SERRULATUS SCORPION-VENOM TOXINS DISPLAY A COMPLEX PATTERN OF ANTIGENIC REACTIVITY

被引：20

作者：

DELIMA, ME

MARTINEAUCLAIRE, MF

CHAVEZOLORTEGUI, C

DINIZ, CR

GRANIER, C

机构：

[1] FAC MED MARSEILLE,BIOCHIM LAB,CNRS,UA 1455,BD PIERRE DRAMARD,F-13326 MARSEILLE 15,FRANCE

[2] INST CIENCIAS BIOL,DEPT BIOQUIM & IMMUNOL,BR-30000 BELO HORIZON,MG,BRAZIL

[3] FDN EZEQUIEL DIAS,BR-30550 BELO HORIZON,MG,BRAZIL

来源：

TOXICON | 1993年 / 31卷 / 02期

关键词：

D O I：

10.1016/0041-0101(93)90290-Y

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The antigenic properties of alpha-type and beta-type toxins purified from Tityus serrulatus (Ts) venom were analysed by radioimmunoassay, using rabbit antibodies raised against Ts VII, the main beta-type toxin in the venom, and against Ts IV, an alpha-type toxin. The anti-Ts VII serum did not recognize either the other beta-toxins Ts I and Ts II or the a-toxin Ts IV; the anti-Ts IV serum did not bind any of the three beta-toxins Ts I, Ts 11 or Ts VII. Thus, Tityus toxins display at least three distinct antigenic reactivity patterns.

引用

页码：223 / 227

页数：5

共 14 条

[1]

BARHANIN J, 1982, J BIOL CHEM, V257, P2553

[2] AMINO-ACID-SEQUENCE OF TOXIN-VII, A BETA-TOXIN FROM THE VENOM OF THE SCORPION TITYUS-SERRULATUS [J].