From virus to vaccine: Developments using the simple eukaryote, Dictyostelium discoideum

被引：7

作者：

Emslie, KR ^{[1
]}

Slade, MB ^{[1
]}

Williams, KL ^{[1
]}

机构：

[1] MACQUARIE UNIV, CTR ANALYT BIOTECHNOL, SCH BIOL SCI, SYDNEY, NSW 2109, AUSTRALIA

来源：

TRENDS IN MICROBIOLOGY | 1995年 / 3卷 / 12期

基金：

澳大利亚研究理事会;

关键词：

D O I：

10.1016/S0966-842X(00)89015-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mass vaccination campaigns against viral diseases, both human and animal, depend on the availability of cheap viral antigens. The eukaryote Dictyostelium discoideum has simple growth requirements and rapid growth rates and forms stable cell lines. These features, together with the possibility of secreting recombinant (glyco)proteins into a defined buffer, make the D. discoideum expression system an attractive option for producing economical recombinant subunit vaccines.

引用

页码：476 / 479

页数：4

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