HYDROXYUREA TREATMENT FOR CHRONIC MYELOID-LEUKEMIA DURING PREGNANCY

被引：54

作者：

JACKSON, N ^{[1
]}

SHUKRI, A ^{[1
]}

ALI, K ^{[1
]}

机构：

[1] HOSP UNIV SAINS MALAYSIA,DEPT OBSTET & GYNAECOL,KUBANG KERIAN 16150,MALAYSIA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1993年 / 85卷 / 01期

关键词：

D O I：

10.1111/j.1365-2141.1993.tb08672.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A patient being treated for chronic myeloid leukaemia with hydroxyurea became pregnant. Despite an increase in the dose of hydroxyurea (to 3 g per day) during the pregnancy, her white blood cell count could only be controlled at about 150 x 10(9)/l. A healthy baby girl was born at 37 weeks with normal blood counts and no evidence of congenital abnormality. There are now five reports of the use of hydroxyurea in pregnancy, and where leucapheresis is not available it may be the treatment of choice.

引用

页码：203 / 204

页数：2

共 12 条

[1] INUTERO MORPHOLOGICAL EFFECTS OF HYDROXYUREA ON THE FETAL DEVELOPMENT IN SPRAGUE-DAWLEY RATS [J].

ASANO, Y ;

OKANIWA, A .

EXPERIMENTAL ANIMALS, 1987, 36 (02) :143-149

[2] INTERFERON-ALPHA THERAPY DURING PREGNANCY IN CHRONIC MYELOGENOUS LEUKEMIA AND HAIRY-CELL LEUKEMIA [J].

BAER, MR ;

OZER, H ;

FOON, KA .

BRITISH JOURNAL OF HAEMATOLOGY, 1992, 81 (02) :167-169

[3] PREGNANCY DURING MYELOSUPPRESSIVE TREATMENT FOR CHRONIC MYELOGENOUS LEUKEMIA [J].

DELMER, A ;

RIO, B ;

BAUDUER, F ;

AJCHENBAUM, F ;

MARIE, JP ;

ZITTOUN, R .

BRITISH JOURNAL OF HAEMATOLOGY, 1992, 82 (04) :783-784

[4]

DIAMOND I, 1960, PEDIATRICS, V25, P85

[5] LEUKAPHERESIS FOR CONTROL OF CHRONIC MYELOGENOUS LEUKEMIA DURING PREGNANCY [J].

FITZGERALD, D ;

ROWE, JM ;

HEAL, J .

AMERICAN JOURNAL OF HEMATOLOGY, 1986, 22 (02) :213-218

[6] EFFECTS OF HYDROXYUREA ON POSTNATAL-GROWTH AND BEHAVIOR OF RATS [J].

FRITZ, H ;

HESS, R .

AGENTS AND ACTIONS, 1980, 10 (04) :389-393

[7]

JOHNSON DF, 1972, AM J OBSTET GYNECOL, V112, P640

[8]

KAPLAN ME, 1986, SEMIN HEMATOL, V23, P167

[9]

MILLER JB, 1976, J REPROD MED, V17, P217

[10] USE OF HYDROXYUREA IN CHRONIC MYELOID-LEUKEMIA DURING PREGNANCY - A CASE-REPORT [J].

PATEL, M ;

DUKES, IAF ;

HULL, JC .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1991, 165 (03) :565-566

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