EXPERIMENTAL AUTOIMMUNE UVEORETINITIS - A MODEL SYSTEM FOR IMMUNOINTERVENTION - A REVIEW

被引：68

作者：

FORRESTER, JV ^{[1
]}

LIVERSIDGE, J ^{[1
]}

DUA, HS ^{[1
]}

DICK, A ^{[1
]}

HARPER, F ^{[1
]}

MCMENAMIN, PG ^{[1
]}

机构：

[1] UNIV WESTERN AUSTRALIA,DEPT ANAT & HUMAN BIOL,NEDLANDS,WA 6009,AUSTRALIA

来源：

CURRENT EYE RESEARCH | 1992年 / 11卷

基金：

英国惠康基金;

关键词：

D O I：

10.3109/02713689208999509

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Experimental autoimmune uveoretinitis (EAU) is a useful model of human posterior uveitis and as such, permits the analysis of strategies for immuno-intervention. Modulation of the autoimmune response may be attempted at the stages of induction of EAU, during homing of autoreactive lymphocytes to the target organ, the retina, or during the effector stage of the disease. This paper presents a brief overview of current immuno-therapeutic modalities and assesses the usefulness for extrapolation to human disease.

引用

页码：33 / 40

页数：8

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