P53 FUNCTION AND DYSFUNCTION

被引：1971

作者：

VOGELSTEIN, B

KINZLER, KW

机构：

来源：

CELL | 1992年 / 70卷 / 04期

关键词：

D O I：

10.1016/0092-8674(92)90421-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：523 / 526

页数：4

共 31 条

[1]

BAKER SJ, 1990, CANCER RES, V50, P7717

[2] WILD-TYPE BUT NOT MUTANT P53 IMMUNOPURIFIED PROTEINS BIND TO SEQUENCES ADJACENT TO THE SV40 ORIGIN OF REPLICATION [J].

BARGONETTI, J ;

FRIEDMAN, PN ;

KERN, SE ;

VOGELSTEIN, B ;

PRIVES, C .

CELL, 1991, 65 (06) :1083-1091

[3] HUMAN P53 IS PHOSPHORYLATED BY P60-CDC2 AND CYCLIN-B-CDC2 [J].

BISCHOFF, JR ;

FRIEDMAN, PN ;

MARSHAK, DR ;

PRIVES, C ;

BEACH, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (12) :4766-4770

[4] CLONAL P53 MUTATION IN PRIMARY CERVICAL-CANCER - ASSOCIATION WITH HUMAN-PAPILLOMAVIRUS-NEGATIVE TUMORS [J].

CROOK, T ;

WREDE, D ;

TIDY, JA ;

MASON, WP ;

EVANS, DJ ;

VOUSDEN, KH .

LANCET, 1992, 339 (8801) :1070-1073

[5] MICE DEFICIENT FOR P53 ARE DEVELOPMENTALLY NORMAL BUT SUSCEPTIBLE TO SPONTANEOUS TUMORS [J].

DONEHOWER, LA ;

HARVEY, M ;

SLAGLE, BL ;

MCARTHUR, MJ ;

MONTGOMERY, CA ;

BUTEL, JS ;

BRADLEY, A .

NATURE, 1992, 356 (6366) :215-221

[6] DEFINITION OF A CONSENSUS BINDING-SITE FOR P53 [J].

ELDEIRY, WS ;

KERN, SE ;

PIETENPOL, JA ;

KINZLER, KW ;

VOGELSTEIN, B .

NATURE GENETICS, 1992, 1 (01) :45-49

[7] TUMORIGENIC POTENTIAL ASSOCIATED WITH ENHANCED EXPRESSION OF A GENE THAT IS AMPLIFIED IN A MOUSE-TUMOR CELL-LINE [J].

FAKHARZADEH, SS ;

TRUSKO, SP ;

GEORGE, DL .

EMBO JOURNAL, 1991, 10 (06) :1565-1569

[8] WILD-TYPE P53 ACTIVATES TRANSCRIPTION INVITRO [J].

FARMER, G ;

BARGONETTI, J ;

ZHU, H ;

FRIEDMAN, P ;

PRYWES, R ;

PRIVES, C .

NATURE, 1992, 358 (6381) :83-86

[9] PRESENCE OF A POTENT TRANSCRIPTION ACTIVATING SEQUENCE IN THE P53 PROTEIN [J].

FIELDS, S ;

JANG, SK .

SCIENCE, 1990, 249 (4972) :1046-1049

[10] A TRANSCRIPTIONALLY ACTIVE DNA-BINDING SITE FOR HUMAN P53 PROTEIN COMPLEXES [J].

FUNK, WD ;

PAK, DT ;

KARAS, RH ;

WRIGHT, WE ;

SHAY, JW .

MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (06) :2866-2871

← 1 2 3 4 →