ENANTIOMERIC DIFFERENTIATION OF A WIDE-RANGE OF PHARMACOLOGICALLY ACTIVE SUBSTANCES BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY USING A BILE-SALT

被引：48

作者：

AUMATELL, A ^{[1
]}

WELLS, RJ ^{[1
]}

机构：

[1] AUSTRALIAN GOVT ANALYT LAB,PYMBLE,NSW 2073,AUSTRALIA

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 688卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(94)00885-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper shows the versatility of modified charged and non-charged beta-cyclodextrins in micellar systems for optically resolving beta-agonists, beta-antagonists, phenylethylamines stimulants and diclofensine an antidepressant. A total of 22 compounds were optically resolved using hydroxypropyl-beta-cyclodextrin with sodium taurodeoxycholate and sodium sulfobutyl ether-beta-cyclodextrin with sodium dodecyl sulfate.

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页码：329 / 337

页数：9

相关论文

共 29 条

[1]

Attwood D., 1983, SURFACTANT SYSTEMS T, P185

[2] ENANTIOMERIC DIFFERENTIATION OF A WIDE-RANGE OF PHARMACOLOGICALLY ACTIVE SUBSTANCES BY CAPILLARY ELECTROPHORESIS USING MODIFIED BETA-CYCLODEXTRINS [J].

AUMATELL, A ;

WELLS, RJ ;

WONG, DKY .

JOURNAL OF CHROMATOGRAPHY A, 1994, 686 (02) :293-307

[3] CHIRAL DIFFERENTIATION OF THE OPTICAL ISOMERS OF RACEMETHORPHAN AND RACEMORPHAN IN URINE BY CAPILLARY ZONE ELECTROPHORESIS [J].

AUMATELL, A ;

WELLS, RJ .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1993, 31 (12) :502-508

[4]

BATCHUNAS AT, 1987, ANAL CHEM, V59, P1466

[5] APPLICATIONS OF MEKC IN THE DETERMINATION OF BENZIDINES FOLLOWING EXTRACTION FROM WATER, SOIL, SEDIMENT, AND CHROMATOGRAPHIC ADSORBENTS [J].

BRUMLEY, WC ;

BROWNRIGG, CM .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1994, 32 (03) :69-75

[6] SODIUM GLYCODEOXYCHOLATE AND TAURODEOXYCHOLATE - POSSIBLE HELICAL MODELS FOR CONJUGATED BILE-SALT MICELLES [J].

CAMPANELLI, AR ;

DESANCTIS, SC ;

CHIESSI, E ;

DALAGNI, M ;

GIGLIO, E ;

SCARAMUZZA, L .

JOURNAL OF PHYSICAL CHEMISTRY, 1989, 93 (04) :1536-1542

[7] DICLOFENSINE AND IMIPRAMINE - A DOUBLE-BLIND COMPARATIVE TRIAL IN DEPRESSIVE OUT-PATIENTS [J].

CAPPONI, R ;

HORMAZABAL, L ;

SCHMIDBURGK, W .

NEUROPSYCHOBIOLOGY, 1985, 14 (04) :173-180

[8] REPRODUCIBLE AND HIGH-SPEED SEPARATION OF BASIC DRUGS BY CAPILLARY ZONE ELECTROPHORESIS [J].

CHEE, GL ;

WAN, TSM .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1993, 612 (01) :172-177

[9] BILE-SALT SURFACTANTS IN MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY - APPLICATION TO HYDROPHOBIC MOLECULE SEPARATIONS [J].

COLE, RO ;

SEPANIAK, MJ ;

HINZE, WL ;

GORSE, J ;

OLDIGES, K .

JOURNAL OF CHROMATOGRAPHY, 1991, 557 (1-2) :113-123

[10]

COLE RO, 1990, HRC-J HIGH RES CHROM, V13, P579