A 3RD HISTAMINE-RECEPTOR SUBTYPE - CHARACTERIZATION, LOCALIZATION AND FUNCTIONS OF THE H3-RECEPTOR

被引：112

作者：

SCHWARTZ, JC

ARRANG, JM

GARBARG, M

POLLARD, H

机构：

[1] Unité de Neurobiologie et Pharmacologie (U. 109) de l'INSERM, Centre Paul Broca, Paris, 75014

来源：

AGENTS AND ACTIONS | 1990年 / 30卷 / 1-2期

关键词：

D O I：

10.1007/BF01968988

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The discovery of the third histamine receptor and the design of highly selective and potent ligands have not only clarified some aspects of histaminergic neurotransmission in brain: they have also provided us with useful experimental tools to modify this neurotransmission and, therefore, to establish more precisely its roles. Furthermore, in analogy with agents interacting with the two other histamine receptor subtypes, it can be safely anticipated that some of these compounds will constitute novel drugs for the therapeutic management of cerebral and peripheral disorders in humans. © 1990 Birkhäuser Verlag.

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页码：13 / 23

页数：11

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