SEPARATION OF A SUBUNIT NECESSARY FOR CDP REDUCTASE FROM OTHER RIBONUCLEOTIDE REDUCTASE ACTIVITIES OF REGENERATING RAT-LIVER

被引:19
作者
YOUDALE, T
MACMANUS, JP
机构
[1] Animal and Cell Physiology Group Division, Biological Sciences National Research Council of Canada Ottawa
关键词
D O I
10.1016/0006-291X(79)90643-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Purification of ribonucleotide reductase from regenerating rat liver using dATP Sepharose chromatography isolated a subunit of the enzyme which was specific for the reduction of CDP. Activities for the other ribonucleotide diphosphates showed differing distribution in the various fractions suggesting different forms of the enzyme for each ribonucleotide diphosphate. © 1979.
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页码:403 / 409
页数:7
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