CHEMOENZYMATIC SYNTHESIS OF PRECURSORS OF FAGOMINE AND 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL

被引：23

作者：

HECQUET, L ^{[1
]}

LEMAIRE, M ^{[1
]}

BOLTE, J ^{[1
]}

DEMUYNCK, C ^{[1
]}

机构：

[1] UNIV CLERMONT FERRAND,CNRS,CHIM ORGAN BIOL LAB,F-63177 CLERMONT FERRAND,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(00)78499-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantioselectivity of transketolase towards, alpha-hydroxy-aldehydes is used to prepare compounds bearing two asymmetric centres, precursors of natural products: 2,3-dideoxynojirimycine (fagomine), 1,4-dideoxy-1,4-imino-D-arabinitol, and its oxidised form.

引用

页码：8791 / 8794

页数：4

共 30 条

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