CYTOCHEMICAL-LOCALIZATION OF ALKALINE-PHOSPHATASE AND NA+-PUMP SITES IN ADULT-RAT COLON

被引:49
作者
VENGESA, PB
HOPFER, U
机构
[1] CASE WESTERN RESERVE UNIV,SCH MED,DEPT ANAT,CLEVELAND,OH 44106
[2] CASE WESTERN RESERVE UNIV,CTR DEV BIOL,CLEVELAND,OH 44106
关键词
D O I
10.1177/27.9.39100
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The cellular and subcellular localization of alkaline and K+-dependent phosphatase activities in the colonic mucosa of adult rats and rabbits was studied with the electron microscope. The 1-cysteine-sensitive alkaline phosphatase activity was observed in the brush border membrane of the chief cells. The contraluminal plasma membrane of chief cells was devoid of this enzyme activity. In contrast, the cardiac glycoside-sensitive K+-dependent phosphatase was predominantly localized in this region of the chief cells.
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页码:1231 / 1235
页数:5
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