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SYNTHESIS OF 3-ARYLMUCONOLACTONES USING BIPHENYL METABOLISM IN ASPERGILLUS
被引:8
作者:
MOBLEY, DP
FINKBEINER, HL
LOCKWOOD, SH
SPIVACK, J
机构:
[1] GE Corporate Research and Development, Schenectady, NY 12301
来源:
关键词:
D O I:
10.1016/S0040-4020(01)90156-5
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
Strains of the fungus Aspergillus form 3-arylmuconolactones as secondary products of the metabolism of biphenyl and substituted biphenyls. The 3-arylmuconolactones are not found to support growth and can accumulate to significant concentrations. The metabolic pathway leading from hydroxylated biphenyls to lactones appears to proceed through 3,4-catechol intermediates.
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页码:3273 / 3280
页数:8
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