SMALL-VOLUME AND LOW FLOW-RATE ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY OF AQUEOUS SAMPLES

被引：177

作者：

GALE, DC ^{[1
]}

SMITH, RD ^{[1
]}

机构：

[1] PACIFIC NW LAB, DEPT CHEM SCI, RICHLAND, WA 99352 USA

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1993年 / 7卷 / 11期

关键词：

D O I：

10.1002/rcm.1290071111

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A new electrospray ionization source (emitter) has been developed which allows the effective utilization of very small sample volumes at much lower flow rates than previously demonstrated. A small diameter etched-tip capillary has been incorporated into a pressure-infusion electrospray ionization source. The ability to electrospray aqueous solutions without the use of an ancillary sheath flow is demonstrated with several biopolymers. High signal intensities and stable signals are observed for this source in a comparison with a standard methanol-sheath source.

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页码：1017 / 1021

页数：5

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