ANISOLE BINDING-PROTEIN FROM DOG OLFACTORY EPITHELIUM

被引：36

作者：

PRICE, S

机构：

[1] Department of Physiology, Medical College of Virginia, Virginia Commonwealth University, Richmond

来源：

CHEMICAL SENSES & FLAVOUR | 1978年 / 3卷 / 01期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1093/chemse/3.1.51

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Extracts of dog olfactory mucosa were subjected to affinity chromatography on columns having exposed methoxyphenyl groups. Elution with p-anisic acid displaced a protein component demonstrable with polyacrylamide gel electrophoresis. This was present in larger amount in extracts made with the detergent, sodium dodecyl sulfate, than in detergent-free extracts, suggesting that it had originated in some membranous structure. It was not seen in extracts of nearby respiratory epithelium. It is hypothesized that this includes a recognition molecule through which odorants such as anisole stimulate olfactory receptors. © 1978 Information Retrieval Limited.

引用

页码：51 / 55

页数：5

共 18 条

[1] SPECIFIC ANOSMIA AND CONCEPT OF PRIMARY ODORS [J].