CARCINOMA OF ENDOMETRIUM IN PREMENOPAUSAL WOMEN

Twenty to 25 per cent of endometrial carcinomas occur in premenopausal women. Insufficient emphasis has been given this in the past. Therefore, delays of many months frequently occur before the origin of abnormal bleeding is clarified among women in their fourth and fifth decades. All cases of premenopausal endometrial carcinoma seen at the Indiana University Medical Center from 1945 through 1966 were reviewed. Diabetes, nulliparity, and obesity were noted to occur with almost the same frequency as among postmenopausal patients with endometrial cancer. Hypertension appeared to be less common in the younger patient but the incidence of thyroid disease seemed to be abnormally high. The absolute 5 year survival rate, among those patients eligible for such an assessment, was 90.2 per cent. © 1969.