DOUBLE-STRANDED-RNA UNWINDING AND MODIFYING ACTIVITY IS DETECTED UBIQUITOUSLY IN PRIMARY TISSUES AND CELL-LINES

被引：94

作者：

WAGNER, RW

YOO, C

WRABETZ, L

KAMHOLZ, J

BUCHHALTER, J

HASSAN, NF

KHALILI, K

KIM, SU

PERUSSIA, B

MCMORRIS, FA

NISHIKURA, K

机构：

[1] WISTAR INST,36TH ST & SPRUCE,PHILADELPHIA,PA 19104

[2] UNIV PENN,DEPT NEUROL,PHILADELPHIA,PA 19104

[3] UNIV PENN,DEPT PEDIAT,PHILADELPHIA,PA 19104

[4] THOMAS JEFFERSON UNIV,DEPT BIOCHEM & MOLEC BIOL,PHILADELPHIA,PA 19107

[5] UNIV HOSP BRITISH COLUMBIA,DEPT MED,DIV NEUROL,VANCOUVER V6T 1W5,BC,CANADA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 10期

关键词：

D O I：

10.1128/MCB.10.10.5586

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A double-stranded RNA unwinding and modifying activity was found to be present in a wide range of tissues and cell types. The level of activity did not vary significantly with respect to the state of cell differentiation, cell cycle, or transformation. Thus, the unwinding and modifying activity, localized in the nucleus in somatic cells and capable of converting many adenosine residues to inosine, appears to be one of the housekeeping genes.

引用

页码：5586 / 5590

页数：5

共 25 条

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