SELF-ORGANIZATION OF POLYMER-MOTOR SYSTEMS IN THE CYTOSKELETON

被引：48

作者：

MITCHISON, TJ

机构：

[1] Department of Pharmacology, University of California, Francisco

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES | 1992年 / 336卷 / 1276期

关键词：

D O I：

10.1098/rstb.1992.0049

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Microtubules and actin filaments are organized into dynamic arrays inside cells. In this paper I discuss in conceptual form the assembly mechanisms of three specific arrays: asters, spindles and leading edge structures. The role of energy transducing processes, particularly motor protein activity, in assembly is explored. I conclude that dynamic interaction between motor proteins and cytoskeletal polymers play a very general role in spatial organization of the cytoplasm.

引用

页码：99 / 106

页数：8

共 39 条

[1] REAL-TIME VISUALIZATION OF CELL-CYCLE DEPENDENT CHANGES IN MICROTUBULE DYNAMICS IN CYTOPLASMIC EXTRACTS
BELMONT, LD
HYMAN, AA
SAWIN, KE
MITCHISON, TJ
[J]. CELL, 1990, 62 (03) : 579 - 589
[2] BUENDIA B, 1990, J CELL SCI, V97, P259
[3] STRUCTURAL POLARITY OF KINETOCHORE MICROTUBULES IN PTK1-CELLS
EUTENEUER, U
MCINTOSH, JR
[J]. JOURNAL OF CELL BIOLOGY, 1981, 89 (02) : 338 - 345
[4] CENTRIPETAL TRANSPORT OF CYTOPLASM, ACTIN, AND THE CELL-SURFACE IN LAMELLIPODIA OF FIBROBLASTS
FISHER, GW
CONRAD, PA
DEBIASIO, RL
TAYLOR, DL
[J]. CELL MOTILITY AND THE CYTOSKELETON, 1988, 11 (04): : 235 - 247
[5] ACTIONS OF CYTOCHALASINS ON THE ORGANIZATION OF ACTIN-FILAMENTS AND MICROTUBULES IN A NEURONAL GROWTH CONE
FORSCHER, P
SMITH, SJ
[J]. JOURNAL OF CELL BIOLOGY, 1988, 107 (04) : 1505 - 1516
[6] MYOSIN-I IS LOCATED AT THE LEADING EDGES OF LOCOMOTING DICTYOSTELIUM AMEBAS
FUKUI, Y
LYNCH, TJ
BRZESKA, H
KORN, ED
[J]. NATURE, 1989, 341 (6240) : 328 - 331
[7] Goldstein L S, 1991, Trends Cell Biol, V1, P93, DOI 10.1016/0962-8924(91)90036-9
[8] ANALYSIS OF THE ROLE OF ASTRAL RAYS IN PRONUCLEAR MIGRATION IN SAND DOLLAR EGGS BY THE COLCEMID-UV METHOD
HAMAGUCHI, MS
HIRAMOTO, Y
[J]. DEVELOPMENT GROWTH & DIFFERENTIATION, 1986, 28 (02) : 143 - 156
[9] ATOMIC MODEL OF THE ACTIN FILAMENT
HOLMES, KC
POPP, D
GEBHARD, W
KABSCH, W
[J]. NATURE, 1990, 347 (6288) : 44 - 49
[10] Inoue S, 1982, DEV ORDER ITS ORIGIN, P35

← 1 2 3 4 →