RECENT STUDIES ON CYTOTOXIC, ANTI-HIV AND ANTIMALARIAL AGENTS FROM PLANTS

被引：11

作者：

CORDELL, GA

ANGERHOFER, CK

PEZZUTO, JM

机构：

[1] Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois

来源：

PURE AND APPLIED CHEMISTRY | 1994年 / 66卷 / 10-11期

关键词：

D O I：

10.1351/pac199466102283

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Plants continue to provide key leading structures and therapeutic agents for a myriad of debilitating diseases. In this presentation, we will discuss the strategies being used, the structure elucidation and spectroscopic assignment of several classes of compounds with cytotoxic, anti-HIV and antimalarial activity, including xanthones and bisbenzylisoquinoline and Amaryllidaceae alkaloids, and we will provide some details of the bioassay systems being used. The application of various one- and two-dimensional nmr techniques to address opportunities for spectroscopic assignment will be described.

引用

页码：2283 / 2286

页数：4

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