COLLABORATIVE STUDY OF THE ANALYSIS OF TYLOSIN BY LIQUID-CHROMATOGRAPHY ON WIDE-PORE POLY(STYRENE-DIVINYLBENZENE)

被引：2

作者：

PAESEN, J

CROMMEN, J

DEBEER, J

JIN, SH

PORQUERAS, E

VANOVERBEKE, A

VIOLON, C

HOOGMARTENS, J

机构：

[1] UNIV LIEGE,INST PHARM,DRUG ANAL LAB,LIEGE,BELGIUM

[2] INST HYG & EPIDEMIOL,B-1050 BRUSSELS,BELGIUM

[3] NATL INST CONTROL PHARMACEUT & BIOL PROD,BEIJING,PEOPLES R CHINA

[4] INST SALUD CARLOS 3,CTR NACL FARMACOBIOL,DEPT BIOL PROD,CONTROL ANTIBIOT LAB,MADRID,SPAIN

[5] STATE UNIV GHENT,FAC FARMACEUT WETENSCHAPPEN,ONTLEDING GENEESMIDDELEN LAB,VAKGRP FARMACEUT ANAL,B-9000 GHENT,BELGIUM

[6] ALGEMENE PHARMACEUT BOND,DIENST GENEESMIDDELENONDERZOEK,BRUSSELS,BELGIUM

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1995年 / 18卷 / 06期

关键词：

D O I：

10.1080/10826079508009284

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A previously developed method for analysis of tylosin A and related substances by liquid chromatography using a wide-pore poly(styrene-divinylbenzene) stationary phase was examined in a multicentre study involving 7 laboratories and 3 samples. The main component and the impurities were determined. An analysis of variance showed absence of consistent laboratory bias and significant laboratory-sample interaction at the 1 % level. Estimates for the repeatability and reproducibility of the method, expressed as standard deviation (SD) of the result of the determination of tylosin A, were calculated to be 1.3 % and 1.6 % respectively.

引用

页码：1195 / 1205

页数：11

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