IDENTIFICATION OF 5' REGULATORY REGIONS OF THE HUMAN CARNITINE PALMITOYLTRANSFERASE-II GENE

被引：8

作者：

MONTERMINI, L ^{[1
]}

WANG, HW ^{[1
]}

VERDERIO, E ^{[1
]}

TARONI, F ^{[1
]}

DIDONATO, S ^{[1
]}

FINOCCHIARO, G ^{[1
]}

机构：

[1] IST NAZL NEUROL,DIV BIOCHIM & GENET,I-20133 MILAN,ITALY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1994年 / 1219卷 / 01期

关键词：

CARNITINE; PROMOTER; INSULIN;

D O I：

10.1016/0167-4781(94)90280-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have identified two partially overlapping genomic clones that contain part of the 5' regulatory region of the human carnitine palmitoyltransferase II gene. The 1.2 kb region upstream the transcription start site, as defined by primer extension experiments, shows promoter activity when inserted upstream of a reporter gene and contains a putative insulin responsive element.

引用

页码：237 / 240

页数：4

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