CHROMATOGRAPHIC RESOLUTION OF THE INTERCONVERTING STEREOISOMERS OF HINDERED SULFINYL AND SULFONYL NAPHTHALENE DERIVATIVES

被引：63

作者：

VILLANI, C ^{[1
]}

PIRKLE, WH ^{[1
]}

机构：

[1] UNIV ILLINOIS,SCH CHEM SCI,URBANA,IL 61801

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0957-4166(94)00343-A

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

1-Naphthyl sulfoxides and sulfones having a beta-methyl group on the aromatic ring show hindered rotation around the C-ar-S bond, giving rise to conformational diastereoisomers and enantiomers, respectively. Low temperature HPLC separation of the interconverting stereoisomers on a recently developed chiral stationary phase is reported; a model to account for the observed sense of chiral recognition is also presented

引用

页码：27 / 30

页数：4

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