MEASUREMENT OF 5-ANDROSTENE-3-BETA, 17-BETA-DIOL IN PLASMA BY RADIOIMMUNOASSAY

被引：16

作者：

MOORE, JW

机构：

[1] Department of Clinical Endocrinology, Imperial Cancer Research Fund, London, WC2A 3PX England, Lincoln's Inn Fields

来源：

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1979年 / 11卷 / 03期

关键词：

D O I：

10.1016/0022-4731(79)90204-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A sensitive and specifie radioimmunoassay for the measurement of 5-androstene-3β 17{amalgamation}-diol (androstenediol) in plasma has been developed using an antiserum against androstenediol-7-carboxymethyloxime conjugated to bovine serum albumin. Plasma samples were extracted in diethylether and chromatographed on Sephadex LH-20 prior to assay. Plasma androstenediol levels were measured in 113 normal women between the ages of 30 and 70 yr. The mean values (±SD) for women in the age ranges 30-50 and 51-70 were 552 ± 223 pg/ml and 401 ± 229 pg/ml respectively. © 1979.

引用

页码：1329 / 1331

页数：3

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