DELAYED GASTRO-INTESTINAL COMPLICATIONS AFTER COMBINED MODALITY THERAPY OF CHILDHOOD RHABDOMYOSARCOMA

被引：21

作者：

RANSOM, JL

NOVAK, RW

KUMAR, APM

HUSTU, HO

PRATT, CB

机构：

[1] St. Jude Children's Research Hospital, Memphis, TN 38101

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1979年 / 5卷 / 08期

关键词：

Childhood rhabdomyosarcoma; Combined modality therapy; Delayed toxicity; Intestinal obstruction;

D O I：

10.1016/0360-3016(79)90653-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Delayed gastrointestinal complications were reviewed following combined modality therapy in 16 children with non-disseminated rhabdomyosarcoma (RMS) involving the retroperitoneum. Six patients experienced severe life-threatening enteritis or proctitis which was documented histologically and occurred in the absence of recurrent tumor; 3 patients subsequently died of small bowel obstruction and attendant complications. These results emphasize a major form of treatment morbidity resulting from the combined use of multiple radiopotentiating agents and therapeutic irradiation of the gastrointestinal tract. © 1979.

引用

页码：1275 / 1279

页数：5