AN IMPROVED SYNTHESIS OF CHIRAL OXAZOLIDINE-2-SELONES - HIGHLY SENSITIVE SE-77 NMR REAGENTS FOR THE DETECTION AND QUANTITATION OF CHIRALITY

被引：45

作者：

SILKS, LA

PENG, J

ODOM, JD

DUNLAP, RB

机构：

[1] Los Alamos National Laboratory, Biochemistry Section and Stable Isotope Resource, INC-4 MS C-346, Los Alamos

[2] Department of Chemistry and Biochemistry, University of South Carolina, Columbia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 24期

关键词：

D O I：

10.1021/jo00024a003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the title compounds from readily available oxazolines has been accomplished in one step in high yield. These chiral reagents exhibit extraordinary Se-77 chemical shift sensitivity and are useful for the detection and quantitation of chirality at remotely disposed chiral centers.

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页码：6733 / 6736

页数：4

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