A SOLUBLE ANTIGEN FLUORESCENT ANTIBODY (SAFA) TEST FOR IMMUNODIAGNOSIS OF TRICHINOSIS IN MAN AND EXPERIMENTAL ANIMALS

被引：13

作者：

GORE, RW

SADUN, EH

机构：

[1] Department of Medical Zoology, Walter Reed Army Institute of Research, Washington

来源：

EXPERIMENTAL PARASITOLOGY | 1968年 / 23卷 / 03期

关键词：

Antigen soluble fluorescent antibody test in trichinosis; Diagnosis; Fluorescent antibody test; Immunodiagnosis of trichinosis; Technics; Trichinella sprialis immunodiagnosis of;

D O I：

10.1016/0014-4894(68)90019-2

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The use of the soluble antigen fluorescent antibody (SAFA) test for the laboratory diagnosis of trichinosis is described. Twenty-six of 28 specimens from humans with proven trichinosis and 2 of 90 specimens from healthy controls reacted in this test. Except for schistosomiasis, reactions with sera from individuals infected with other parasitic agents rarely occurred. Elution of dried blood specimens obtained on absorbent paper could be tested satisfactorily by this technic. Results with mice, rats, and rabbits experimentally infected with single and multiple doses of Trichinella spiralis larvae showed that SAFA antibodies could be detected 2 weeks after inoculation and reached a peak 4-5 weeks later. A high antibody titer was sustained until the end of the experiment, approximately 8 months after infection. © 1968.

引用

页码：287 / +

页数：1

共 25 条

[21] INDIRECT FLUORESCENT ANTIBODY TESTS FOR PARASITIC DISEASES .I. PREPARATION OF A STABLE ANTIGEN FROM LARVAE OF TRICHINELLA SPIRALIS [J].