INDUCTION OF GLUTATHIONE-S-TRANSFERASE ISOENZYMES BY PROTEIN-A IN RAT-LIVER

被引：8

作者：

DWIVEDI, PP

KUMAR, A

PRASAD, AK

PANDYA, KP

RAY, PK

机构：

[1] Industrial Toxicology Research Centre, Lucknow, 226001

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 169卷 / 02期

关键词：

D O I：

10.1016/0006-291X(90)90356-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The administration of Protein A, a cell wall protein of Staphylococcus aureus Cowan I cells, causes an induction of glutathione-s-transferase in rat liver. Proteins, cross reactive with anti human glutathione-s-transferase, acidic (π), basic (α) and neutral (μ) isoenzymes, are induced by 5.8, 2.2 and 6.15 fold respectively. The induction of glutathione -s-transferases, at least in part, might play a role in manifestation of therapeutic properties of Protein A. © 1990.

引用

页码：476 / 481

页数：6

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