INDUCTION OF GLUTATHIONE-S-TRANSFERASE ISOENZYMES BY PROTEIN-A IN RAT-LIVER

被引：8

作者：

DWIVEDI, PP

KUMAR, A

PRASAD, AK

PANDYA, KP

RAY, PK

机构：

[1] Industrial Toxicology Research Centre, Lucknow, 226001

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 169卷 / 02期

关键词：

D O I：

10.1016/0006-291X(90)90356-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The administration of Protein A, a cell wall protein of Staphylococcus aureus Cowan I cells, causes an induction of glutathione-s-transferase in rat liver. Proteins, cross reactive with anti human glutathione-s-transferase, acidic (π), basic (α) and neutral (μ) isoenzymes, are induced by 5.8, 2.2 and 6.15 fold respectively. The induction of glutathione -s-transferases, at least in part, might play a role in manifestation of therapeutic properties of Protein A. © 1990.

引用

收藏

页码：476 / 481

页数：6

相关论文

共 20 条

[11] RELATIVE INDUCTION OF MOLECULAR-FORMS OF CYTOCHROME-P-450 IN GAMMA-HEXACHLOROCYCLOHEXANE EXPOSED RAT-LIVER MICROSOMES [J].

KUMAR, A ;

DWIVEDI, PP .

ARCHIVES OF TOXICOLOGY, 1988, 62 (06) :479-481

[12] IDENTIFICATION OF 3 CLASSES OF CYTOSOLIC GLUTATHIONE TRANSFERASE COMMON TO SEVERAL MAMMALIAN-SPECIES - CORRELATION BETWEEN STRUCTURAL DATA AND ENZYMATIC-PROPERTIES [J].

MANNERVIK, B ;

ALIN, P ;

GUTHENBERG, C ;

JENSSON, H ;

TAHIR, MK ;

WARHOLM, M ;

JORNVALL, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (21) :7202-7206

[13] INCREASED MACROPHAGE ACTIVITY IN PROTEIN A TREATED TUMOR REGRESSED ANIMALS [J].

PRASAD, AK ;

SINGH, KP ;

SAXENA, AK ;

MATHUR, NK ;

RAY, PK .

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 1987, 9 (04) :541-561

[14]

Ray PK, 1981, IMMUNE COMPLEXES PLA, P197

[15]

RAY PK, 1983, IMMUNOL COMMUN, V12, P456

[16]

RAY PK, 1985, CANCER CHEMOTHER PHA, V4, P59

[17]

SAHA S, 1987, INDIAN J EXP BIOL, V25, P514

[18] PURIFICATION, INDUCTION, AND DISTRIBUTION OF PLACENTAL GLUTATHIONE TRANSFERASE - A NEW MARKER ENZYME FOR PRENEOPLASTIC CELLS IN THE RAT CHEMICAL HEPATOCARCINOGENESIS [J].

SATOH, K ;

KITAHARA, A ;

SOMA, Y ;

INABA, Y ;

HATAYAMA, I ;

SATO, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (12) :3964-3968

[19] PROTECTION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY BY PROTEIN-A [J].

SINGH, KP ;

SAXENA, AK ;

ZAIDI, SIA ;

DWIVEDI, PD ;

SRIVASTAVA, SP ;

SETH, PK ;

RAY, PK .

JOURNAL OF APPLIED TOXICOLOGY, 1988, 8 (06) :407-410

[20] EFFICIENT ISOLATION OF GENES BY USING ANTIBODY PROBES [J].

YOUNG, RA ;

DAVIS, RW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (05) :1194-1198