SEQUENCE POLYMORPHISM OF AMB-A-I AND AMB-A-II, THE MAJOR ALLERGENS IN AMBROSIA-ARTEMISIIFOLIA (SHORT RAGWEED)

被引：56

作者：

GRIFFITH, IJ ^{[1
]}

POLLOCK, J ^{[1
]}

KLAPPER, DG ^{[1
]}

ROGERS, BL ^{[1
]}

NAULT, AK ^{[1
]}

机构：

[1] UNIV N CAROLINA,SCH MED,DEPT MICROBIOL & IMMUNOL,CHAPEL HILL,NC 27514

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1991年 / 96卷 / 04期

关键词：

D O I：

10.1159/000235512

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Two of the major allergens in the pollen of short ragweed are Amb a I and Amb a II (formerly antigen E and antigen K, respectively). The genes for Amb a I and Amb a II have recently been cloned, and it was shown that Amb a I is a family of proteins with at least three distinct polymorphic family members. This study addresses the number of individual Amb a I and Amb a II family members, the polymorphism in each family member and the expression of these genes in ragweed plants from different geographical locations. This work led to the cloning and characterization of a fourth Amb a I family member, designated Amb a I.4.

引用

页码：296 / 304

页数：9

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