HEMATOLOGICAL-CHANGES PRODUCED IN MICE BY OCHRATOXIN-A

被引：21

作者：

GUPTA, M

BANDOPADHYAY, S

PAUL, B

MAJUMDER, SK

机构：

[1] Division of Pharmacology, Department of Pharmacy, Jadavpur University, Calcultta

来源：

TOXICOLOGY | 1979年 / 14卷 / 01期

关键词：

D O I：

10.1016/0300-483X(79)90095-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effects of ochratoxin A (5 mg/kg, intraperitoneal) on clotting time, hemoglobin, total count of red blood cells and white blood cells and differential count of white blood cells were studied in mice. This mycotoxin caused a significant decrease in the hemaglobin level and in the total count of red blood cells. Among white blood cells there was a significant increase in small lymphocytes and a significant fall in the count of neutrophils, basophils and monocytes in treated mice. The administration of ochratoxin A also prolonged the clotting time by more than 6-fold. © 1979.

引用

页码：95 / 98

页数：4