ANNEXIN-VI HAS TUMOR-SUPPRESSOR ACTIVITY IN HUMAN A431 SQUAMOUS EPITHELIAL CARCINOMA-CELLS

被引：51

作者：

THEOBALD, J

HANBY, A

PATEL, K

MOSS, SE

机构：

[1] UNIV LONDON UNIV COLL,DEPT PHYSIOL,LONDON WC1E 6BT,ENGLAND

[2] IMPERIAL CANC RES FUND,HISTOPATHOL UNIT,LONDON WC2A 3PN,ENGLAND

来源：

BRITISH JOURNAL OF CANCER | 1995年 / 71卷 / 04期

关键词：

ANNEXIN; TUMOR SUPPRESSION; CALCIUM BINDING PROTEIN;

D O I：

10.1038/bjc.1995.152

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this study we show that heterologous expression of annexin VI in A431 squamous carcinoma cells caused a marked suppression of tumour cell growth when cells were cultured subcutaneously in nude mice. The tumours formed by the annexin VI+ A431 cells were morphologically and histologically similar to those formed by the wild-type cells.

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收藏

页码：786 / 788

页数：3

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