STRUCTURE AND EXPRESSION OF THE HAIRLESS GENE OF MICE

被引：150

作者：

CACHONGONZALEZ, MB

FENNER, S

COFFIN, JM

MORAN, C

STOYE, JP

BEST, S

机构：

[1] NATL INST MED RES, LONDON NW7 1AA, ENGLAND

[2] TUFTS UNIV, SCH MED, DEPT MOLEC BIOL & MICROBIOL, BOSTON, MA 02111 USA

[3] UNIV SYDNEY, DEPT ANIM SCI, SYDNEY, NSW 2006, AUSTRALIA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1994年 / 91卷 / 16期

关键词：

D O I：

10.1073/pnas.91.16.7717

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The hairless mutation of mice was caused by insertion of a murine leukemia virus. Starting with sequences flanking the provirus, a series of overlapping clones surrounding the viral integration site were obtained. By using a combination of sequencing, PCR, and exon-trapping techniques, the hairless gene was identified. It encodes a predicted protein of 1182 amino acids, including a potential zinc finger domain. The expression patterns of the gene closely reflect the phenotype of animals carrying the hairless mutation.

引用

页码：7717 / 7721

页数：5

共 37 条

[11] NIT-2, THE MAJOR NITROGEN REGULATORY GENE OF NEUROSPORA-CRASSA, ENCODES A PROTEIN WITH A PUTATIVE ZINC FINGER DNA-BINDING DOMAIN
FU, YH
MARZLUF, GA
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (03) : 1056 - 1065
[12] CHARACTERIZATION AND HISTOGENESIS OF TUMORS IN THE HAIRLESS MOUSE PRODUCED BY LOW-DOSAGE INCREMENTAL ULTRAVIOLET-RADIATION
GALLAGHER, CH
CANFIELD, PJ
GREENOAK, GE
REEVE, VE
[J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1984, 83 (03) : 169 - 174
[13] THE SECRET LIFE OF THE HAIR FOLLICLE
HARDY, MH
[J]. TRENDS IN GENETICS, 1992, 8 (02) : 55 - 61
[14] DIFFERENTIAL TRANSCRIPTION FROM THE LONG TERMINAL REPEATS OF INTEGRATED AVIAN-LEUKOSIS VIRUS-DNA
HERMAN, SA
COFFIN, JM
[J]. JOURNAL OF VIROLOGY, 1986, 60 (02) : 497 - 505
[15] MUTATIONS AT THE MOUSE MICROPHTHALMIA LOCUS ARE ASSOCIATED WITH DEFECTS IN A GENE ENCODING A NOVEL BASIC-HELIX-LOOP-HELIX-ZIPPER PROTEIN
HODGKINSON, CA
MOORE, KJ
NAKAYAMA, A
STEINGRIMSSON, E
COPELAND, NG
JENKINS, NA
ARNHEITER, H
[J]. CELL, 1993, 74 (02) : 395 - 404
[16] ANALYSIS OF A MURINE MALE GERM CELL-SPECIFIC TRANSCRIPT THAT ENCODES A PUTATIVE ZINC FINGER PROTEIN
HOOG, C
SCHALLING, M
GRUNDERBRUNDELL, E
DANEHOLT, B
[J]. MOLECULAR REPRODUCTION AND DEVELOPMENT, 1991, 30 (03) : 173 - 181
[17] IVERSEN U, 1976, CANCER RES, V36, P1238
[18] RESPONSE OF MURINE EPIDERMIS TO 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN - INTERACTION OF THE AH AND HR LOCI
KNUTSON, JC
POLAND, A
[J]. CELL, 1982, 30 (01) : 225 - 234
[19] AN ANALYSIS OF 5'-NONCODING SEQUENCES FROM 699 VERTEBRATE MESSENGER-RNAS
KOZAK, M
[J]. NUCLEIC ACIDS RESEARCH, 1987, 15 (20) : 8125 - 8148
[20] THE REGULATORY GENE AREA MEDIATING NITROGEN METABOLITE REPRESSION IN ASPERGILLUS-NIDULANS - MUTATIONS AFFECTING SPECIFICITY OF GENE ACTIVATION ALTER A LOOP RESIDUE OF A PUTATIVE ZINC FINGER
KUDLA, B
CADDICK, MX
LANGDON, T
MARTINEZROSSI, NM
BENNETT, CF
SIBLEY, S
DAVIES, RW
ARST, HN
[J]. EMBO JOURNAL, 1990, 9 (05) : 1355 - 1364

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